Impact of Concomitant Aberrant CD200 and BCL2 Overexpression on Outcome of Acute Myeloid Leukemia: A Cohort Study from a Single Center

Mario TiribelliAngela MicheluttiMargherita CavallinSara Di GiustoRenato FaninDaniela Damiani

Published in: Turkish journal of haematology : official journal of Turkish Society of Haematology (2021)

Our data support a synergistic effect of CD200 and BCL2 in AML cells, conferring an enhanced survival capacity in a permissive microenvironment and resulting in worse prognosis.

Keyphrases

acute myeloid leukemia
induced apoptosis
allogeneic hematopoietic stem cell transplantation
stem cells
nk cells
cell cycle arrest
electronic health record
transcription factor
signaling pathway
machine learning
deep learning