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PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic Autoimmunity.

Christopher P HaycookJoseph A BalsamoEvan B GlassCharles H WilliamsCharles C HongAmy S MajorTodd D Giorgio
Published in: International journal of nanomedicine (2020)
This work is the first characterization of Egm's immunomodulatory potential. Importantly, this study also suggests the potential benefit of a biodegradable delivery vehicle that is rationally designed for preferential interaction with a specific immune cell subtype for targeted modulation of Hh signaling.
Keyphrases
  • drug delivery
  • rheumatoid arthritis
  • cancer therapy
  • human health
  • climate change
  • bone regeneration