PEGylated PLGA Nanoparticle Delivery of Eggmanone for T Cell Modulation: Applications in Rheumatic Autoimmunity.
Christopher P HaycookJoseph A BalsamoEvan B GlassCharles H WilliamsCharles C HongAmy S MajorTodd D GiorgioPublished in: International journal of nanomedicine (2020)
This work is the first characterization of Egm's immunomodulatory potential. Importantly, this study also suggests the potential benefit of a biodegradable delivery vehicle that is rationally designed for preferential interaction with a specific immune cell subtype for targeted modulation of Hh signaling.