Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma.

Ming SunYingying CaoReona OkadaJeyshka M Reyes-GonzálezHannah G StackHaiying QinNan LiCharlie SeibertMichael C KellyFiorella SchischlikMitchell HoCarol J ThieleRosa Nguyen

Published in: Journal for immunotherapy of cancer (2023)

Given the robust preclinical activity of CT3.28H.BBζ, these results form a promising basis for further clinical testing in children with NB.

Keyphrases

cell therapy
young adults
computed tomography
image quality
growth factor
dual energy
contrast enhanced
cancer therapy
magnetic resonance imaging
drug delivery
mesenchymal stem cells