Downregulation of CYP39A1 Serves as a Novel Biomarker in Hepatocellular Carcinoma with Worse Clinical Outcome.

Dan LiTao YuJunjie HuJie WuShi FengQingxue XuHua ZhuXu ZhangYonggang ZhangBenHong ZhouLijuan Gu Zhi Zeng

Published in: Oxidative medicine and cellular longevity (2021)

Downregulation of CYP39A1 is associated with HCC carcinogenesis, tumor differentiation, and poor overall survival, suggesting that CYP39A1 may serve as a tumor suppressor gene and novel biomarker for HCC patients.

Keyphrases

end stage renal disease
cell proliferation
newly diagnosed
signaling pathway
chronic kidney disease
peritoneal dialysis
prognostic factors
copy number
dna methylation
transcription factor
free survival