Login / Signup

Dopamine pathway and Parkinson's risk variants are associated with levodopa-induced dyskinesia.

Yuri L SoseroSara Bandres-CigaBart FerwerdaMaria T P TocinoDìaz R BellosoPilar Gómez-GarreJohann FaouziPille TabaLukas PavelkaTainà M MarquesClarissa P C GomesAlexey KolodkinPatrick MayLukasz M MilanowskiZbigniew K WszolekRyan J UittiPeter HeutinkJacobus J van HiltenDavid K SimonShirley EberlyIgnacio AlvarezLynne KrohnEric YuKathryn FreemanUladzislau RudakouJennifer A RuskeyFarnaz AsayeshManuel Menéndez-GonzàlezPau PastorOwen A RossRejko KrügerJean-Christophe CorvolSulev KõksPablo MirRob M A de BieHirotaka IwakiZiv Gan-Or
Published in: medRxiv : the preprint server for health sciences (2023)
This study suggests that variants implicated in PD and in the dopaminergic transmission pathway play a role in the risk/time to develop LID. Further studies will be necessary to examine how these findings can inform clinical care.
Keyphrases
  • copy number
  • healthcare
  • palliative care
  • high glucose
  • parkinson disease
  • quality improvement
  • pain management
  • uric acid
  • oxidative stress
  • drug induced
  • endothelial cells
  • chronic pain