Correlation between breast cancer subtypes determined by immunohistochemistry and n-COUNTER PAM50 assay: a real-world study.
Sara Lopez-TarruellaMaría Del Monte-MillánMarta Roche-MolinaYolanda JerezIsabel Echavarria Diaz-GuardaminoBlanca Herrero LópezSalvador Gamez CasadoIván Marquez-RodasEnrique AlvarezMaría CebolleroTatiana MassarrahInmaculada OcañaAinhoa AriasJosé Ángel García-SáenzFernando Moreno AntonClara Olier GarateDiana Moreno MuñozDavid MarrupeMiguel Ángel Lara ÁlvarezSantos EnrechCoralia Bueno MuiñoMiguel MartinPublished in: Breast cancer research and treatment (2023)
The concordance between luminal subtypes determined by three different IHC-based classifiers and the nCOUNTER PAM50 assay was suboptimal. Thus, a significant proportion of luminal A and B tumors as determined by the surrogate classifiers could be undertreated or over-treated.
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