BE-FLARE: a fluorescent reporter of base editing activity reveals editing characteristics of APOBEC3A and APOBEC3B.

Matthew A CoelhoSongyuan LiLuna Simona PaneMike FirthGiovanni CiottaJonathan D WrigleyMaria Emanuela CuomoMarcello MarescaBenjamin J M Taylor

Published in: BMC biology (2018)

Using BE-FLARE to report on the efficiency and precision of editing events, we outline workflows for the accelerated generation of genetically engineered cell models and the discovery of alternative base editors.

Keyphrases

crispr cas
small molecule
single cell
quantum dots
cell therapy