Impaired Mitochondrial Respiration in REM-Sleep Behavior Disorder: A Biomarker of Parkinson's Disease?

Gerardo OngariCristina GhezziDeborah Di Martino Antonio Pisani Michele Terzaghi Micol Avenali Enza Maria Valente Silvia Cerri Fabio Blandini

Published in: Movement disorders : official journal of the Movement Disorder Society (2023)

Altogether, these findings suggest that mitochondrial dysfunctions in individuals with iRBD might predispose to worsening of the bioenergetic profile observed in RBD-PD patients, highlighting these alterations as potential predictors of phenoconversion to PD. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Keyphrases

end stage renal disease
oxidative stress
ejection fraction
newly diagnosed
chronic kidney disease
risk assessment
climate change