Validation of differentially expressed brain-enriched microRNAs in the plasma of PD patients.
Stylianos RavanidisAnastasia BougeaNikolaos PapagiannakisChristos KorosAthina Maria SimitsiIoanna PachiMarianthi BrezaLeonidas StefanisEpaminondas DoxakisPublished in: Annals of clinical and translational neurology (2020)
We validated a panel of brain-enriched miRNAs that can be used along with other measures for the detection of PD, revealed molecular pathways targeted by these deregulated miRNAs, and identified upstream transcription factors that may be directly implicated in PD pathogenesis.