The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients.

Smith WanmasaeWisant SirintronsoponSureerut PorntadavityNutjaree Jeenduang

Published in: Cardiovascular therapeutics (2017)

APOE4 carriers and the CETP TaqIB B2B2 genotype were associated with a decreased response, but PCSK9 474IV carriers tended to be associated with an increased response to simvastatin therapy in Thai hypercholesterolemic patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
cognitive decline
metabolic syndrome
patient reported outcomes
mesenchymal stem cells
bone marrow
patient reported