Phenome-wide screening of GWAS data reveals the complex causal architecture of obesity.

Luis M García-Marín Adrian I Campos Pik-Fang Kho Nicholas G Martin Gabriel Cuellar-Partida Miguel E Renteria

Published in: Human genetics (2021)

Our results indicate that obesity causally affects a wide range of traits and comorbid diseases, thus providing an overview of the metabolic, physiological, and neuropsychiatric impact of obesity on human health.

Keyphrases

insulin resistance
human health
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
risk assessment
climate change
gene expression
genome wide
skeletal muscle
body mass index
dna methylation