Examining the Genetic Links between Clusters of Immune-mediated Diseases and Psychiatric Disorders.
Sophie BreunigYounga Heather LeeElizabeth W KarlsonArjun KrishnanJeremy M LawrenceLukas S SchafferAndrew D GrotzingerPublished in: medRxiv : the preprint server for health sciences (2024)
Our results revealed genetic links between clusters of immune-mediated diseases and psychiatric disorders. Current analyses indicate that previously described relationships between specific psychiatric disorders and immune-mediated diseases often capture broader pathways of risk sharing indexed by our genomic factors, yet are more specific than a general association across all psychiatric disorders and immune-mediated diseases.
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