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Metabolically Abnormal Obesity Increases the Risk of Advanced Prostate Cancer in Chinese Patients Undergoing Radical Prostatectomy.

Wen LiuWenxian LiZhankun WangYao ZhuDingwei YeGuiming Zhang
Published in: Cancer management and research (2020)
The MAO phenotype is associated with aggressive PCa, including a higher prostatectomy Gleason score, pathological stage, and seminal vesicle invasion and might also be associated with disease progression. Obesity and metabolic disorders act synergistically to increase the pathological risk of PCa.
Keyphrases
  • radical prostatectomy
  • prostate cancer
  • insulin resistance
  • metabolic syndrome
  • patients undergoing
  • weight loss
  • type diabetes
  • high fat diet induced
  • weight gain
  • skeletal muscle
  • minimally invasive