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Epilepsy as a systemic condition: Link with somatic comorbidities.

Jan NovyG S BellJ L PeacockS M SisodiyaJ W Sander
Published in: Acta neurologica Scandinavica (2017)
Somatic comorbidities do not occur randomly in relation to epilepsy; having more severe epilepsy seems to be a risk factor. Independently from age, the early period after epilepsy onset appears to be at particular risk, although it is not clear whether this relates to an early mortality or to a later decrease in the burden of comorbidities. These results suggest that, for some people, epilepsy should be considered a systemic condition not limited to the CNS.
Keyphrases
  • risk factors
  • temporal lobe epilepsy
  • cardiovascular disease
  • copy number
  • cardiovascular events
  • type diabetes
  • blood brain barrier
  • gene expression
  • early onset