CircZNF609 regulates pulmonary fibrosis via miR-145-5p/KLF4 axis and its translation function.

Wenqing SunSiyun ZhouLan PengYi LiuDemin ChengYue WangChunhui Ni

Published in: Cellular & molecular biology letters (2023)

Our data indicate that circZNF609 is a critical regulator of fibroblast activation and silica-induced lung fibrosis. The circZNF609 and its derived peptides may represent novel promising targets for the treatment of pulmonary fibrosis.

Keyphrases

pulmonary fibrosis
transcription factor
electronic health record
big data
combination therapy
deep learning