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Biological Activity of Novel Pyrrole Derivatives as Antioxidant Agents Against 6-OHDA Induced Neurotoxicity in PC12 Cells.

Hanieh JavidEbrahim Saeedian MoghadamMaryam FarahmandfarMahboubeh ManouchehrabadiMohsen AminiMona SalimiAnahita Torkaman-Boutorabi
Published in: Iranian journal of pharmaceutical research : IJPR (2023)
These findings suggest that the novel synthetic pyrrolic derivatives may be considered promising neuroprotective agents that can potentially prevent the progression of PD.
Keyphrases
  • diabetic rats
  • high glucose
  • oxidative stress
  • anti inflammatory
  • drug induced
  • brain injury
  • structure activity relationship