Ebola Virus Disease Features Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome in the Rhesus Macaque Model.

David X LiuBapi PaharTimothy K CooperDonna L PerryHuanbin XuLouis M HuzellaRicky D AdamsAmanda M W HischakRandy J HartRebecca BernbaumDeja RiveraScott AnthonyMarisa St ClaireRussell ByrumKurt CooperRebecca ReederJonathan KurtzKyra HadleyJiro WadaIan CrozierGabriella WorwaRichard S BennettTravis WarrenMichael R HolbrookConnie S SchmaljohnLisa E Hensley

Published in: The Journal of infectious diseases (2023)

Our data suggest that EVD in the rhesus macaque model mimics pathophysiologic features of HLS/MAS. Hence, regulating inflammation and immune function might provide an effective treatment for controlling acute EVD pathogenesis.

Keyphrases

liver failure
adipose tissue
respiratory failure
big data
intensive care unit
electronic health record