Coagulopathy: Another side effect of coronavirus infection.
Fatemeh SadoughiParisa Maleki DanaJamal HalajzadehZatollah AsemiMohammad Ali MansourniaBahman YousefiPublished in: Journal of cardiovascular and thoracic research (2020)
Recently, coronavirus disease 2019 (COVID-19) has been considered as a major health problem around the globe. This severe acute respiratory syndrome has a bunch of features, such as high transmission rate, which are adding to its importance. Overcoming this disease relies on a complete understanding of the viral structure, receptors, at-risk cells or tissues, and pathogenesis. Currently, researches have shown that besides the lack of a proper anti-viral therapeutic method, complications provided by this virus are also standing in the way of decreasing its mortality rate. One of these complications is believed to be a hematologic manifestation. Commonly, three kinds of coagulopathies are detected in COVID-19 patients: disseminated intravascular coagulation (DIC), pulmonary embolism (PE), and deep vein thrombosis (DVT). In this paper, we have reviewed the relation between these conditions and coronavirus-related diseases pathogenesis, severity, and mortality rate.
Keyphrases
- sars cov
- pulmonary embolism
- coronavirus disease
- respiratory syndrome coronavirus
- risk factors
- cardiovascular events
- healthcare
- inferior vena cava
- induced apoptosis
- public health
- mental health
- coronary artery
- gene expression
- cell cycle arrest
- cardiovascular disease
- cell proliferation
- health information
- cell death
- social media
- climate change