Intensive Ambulance-Delivered Blood-Pressure Reduction in Hyperacute Stroke.
Gang LiYapeng LinJie YangCraig S AndersonChen ChenFeifeng LiuLaurent BillotQiang LiXiaoying ChenXiaoqiu LiuXinwen RenChunfang ZhangPing XuLijun WuFeng WangDaijun QiuMei JiangYiqian PengChaohui LiYiyang HuangXiaohui ZhaoJiye LiangYao WangXiangjun WuXiaoyun XuGuofang ChenDongya HuangYue ZhangLian ZuoGuozhao MaYumei YangJunjie HaoXiahong XuXinli XiongYueyu TangYijia GuoJianping YuShuping LiSong HeFengkai MaoQuandan TanSong TanNengwei YuRuxiang XuMingwei SunBinghu LiJiang GuoLeibo LiuHueiming LiuMenglu OuyangPhilip M BathHisatomi ArimaGary A FordThompson RobinsonElse Charlotte SandsetJeffrey L SaverNikola SpriggH Bart van der WorpLili Songnull nullPublished in: The New England journal of medicine (2024)
In this trial, prehospital blood-pressure reduction did not improve functional outcomes in a cohort of patients with undifferentiated acute stroke, of whom 46.5% subsequently received a diagnosis of hemorrhagic stroke. (Funded by the National Health and Medical Research Council of Australia and others; INTERACT4 ClinicalTrials.gov number, NCT03790800; Chinese Trial Registry number, ChiCTR1900020534.).