Reply to Comment on "Reproducibility study of Monte Carlo simulations for nanoparticle dose enhancement and biological modeling of cell survival curves" [Biomed Phys Eng Express 2023;9:045004].

Rabus has highlighted several important aspects on the use of the local effect model for which we are very grateful, specifically the reduction from 3D to 2D. We discuss how our approach can be modified to fall in line with the submitted comments and also discuss concerns regarding "macroscopic dose estimates".