Salvianolic Acid B Alleviates Heart Failure by Inactivating ERK1/2/GATA4 Signaling Pathway after Pressure Overload in Mice.
Juan YuRenshan ChenYafang TanJiashin WuJianyong QiMinzhou ZhangWeiwang GuPublished in: PloS one (2016)
Our data provide a mechanism of inactivating the ERK1/2/GATA4 signaling pathway for SalB inhibition of the TAC-induced HF.
Keyphrases
- signaling pathway
- pi k akt
- heart failure
- transcription factor
- induced apoptosis
- epithelial mesenchymal transition
- acute heart failure
- high glucose
- diabetic rats
- electronic health record
- cell proliferation
- high fat diet induced
- big data
- oxidative stress
- mouse model
- metabolic syndrome
- endothelial cells
- deep learning
- artificial intelligence