A Computational Approach Using Bioinformatics to Screening Drug Targets for Leishmania infantum Species.
Miguel Angel Chávez-FumagalliMônica Santos SchneiderDaniela Pagliara LageGrasiele de Sousa Vieira TavaresDébora Vasconcelos Costa MendonçaThaís Teodoro de Oliveira SantosRodrigo Maia PáduaRicardo Andrez Machado-de-ÁvilaJoão Paulo Viana LeiteEduardo Antônio Ferraz CoelhoPublished in: Evidence-based complementary and alternative medicine : eCAM (2018)
In this context, this study provides the basis for understanding the mechanism of action of strychnobiflavone in L. infantum and presents a strategy based on bioinformatics programs to screen targets of other molecules with biological action against distinct pathogens.