RNA-sequencing of paired tape-strips and skin biopsies in atopic dermatitis reveals key differences.
Blaine Gabriel FritzAnne-Sofie HallingIsabel Díaz-Pinés CortMaria Oberlander ChristensenAmalie Thorsti Møller RønnstadCaroline Meyer OlesenMette Hjorslev KnudgaardClaus ZachariaeSteffen HeegaardJacob Pontoppidan ThyssenThomas BjarnsholtPublished in: Allergy (2024)
This study concludes that tape-strips and biopsies each demonstrate respective advantages for measuring gene-expression changes in AD. Thus, the specific skin layers and genes of interest should be considered before selecting either method.