Efficacy of transurethral botulinum toxin A injections for bladder outlet obstruction: A systematic review and meta-analysis.
Filippo GaviRagonese MauroDaniele FettucciariRiccardo BientinesiCarlo GandiCampetella MarcoFilippo MarinoMarco RacioppiEmilio SaccoNazario FoschiPublished in: Urologia (2024)
In conclusion, transurethral BoNT-A injections have been shown to improve LUTS, QoL, and urodynamic parameters of individuals with BOO at 3 and 6 months after injections, and no serious adverse effects have been reported. However, data on the long-term benefits of this treatment are scarce, and more prospective, randomized studies with larger samples examining various injection techniques, dosages, and extended follow-up of recurrent injections are needed.
Keyphrases
- ultrasound guided
- platelet rich plasma
- benign prostatic hyperplasia
- lower urinary tract symptoms
- botulinum toxin
- open label
- double blind
- spinal cord injury
- muscle invasive bladder cancer
- electronic health record
- phase iii
- clinical trial
- machine learning
- placebo controlled
- combination therapy
- smoking cessation
- urinary incontinence