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The evolution of pharmacovigilance ecosystems: Does Moore's law invite the use of Occam's razor?

Marion MuellerDavid John LewisAmalia Alexe
Published in: British journal of clinical pharmacology (2022)
We summarize the current characterization of safety data types, sources and the classification of these data. Using this benchmark, we discuss the future requirements of an effective pharmacovigilance ecosystem, keeping the principle of parsimony in mind. In this complex, continuously and rapidly changing environment, there is a need for a return to simplicity and pragmatism. The application of Occam's razor could help to support the rapid provision of new, affordable medicines with a positive benefit to risk profile.
Keyphrases
  • climate change
  • electronic health record
  • adverse drug
  • big data
  • machine learning
  • drug induced
  • deep learning
  • palliative care
  • current status
  • emergency department
  • human health