Coagulation factor VIII: Relationship to cardiovascular disease risk and whole genome sequence and epigenome-wide analysis in African Americans.

Laura M RaffieldAke T LuMindy D SzetoAmarise LittleKelsey E GrindeJessica ShawPaul L AuerAndrea N EdgintonSteve HorvathMarguerite R IrvinEthan M LangeLeslie A LangeDeborah A NickersonTimothy A ThorntonJames G WilsonMarsha M Wheelernull nullNeil A ZakaiAlex P Reiner

Published in: Journal of thrombosis and haemostasis : JTH (2020)

Larger sample sizes of AAs will be required to discover additional genetic and epigenetic contributors to FVIII phenotypic variation, which may have consequences for CVD health disparities.

Keyphrases

cardiovascular disease
dna methylation
healthcare
public health
genome wide
gene expression
type diabetes
health information
copy number
metabolic syndrome
cardiovascular events
health promotion
coronary artery disease
cardiovascular risk factors
human health
risk assessment
affordable care act
health insurance