Polymorphism of CD14 Gene Is Associated with Adverse Outcome among Patients Suffering from Cardiovascular Disease.
Susanne SchulzMartin ZielskeSascha SchneiderBritt HofmannHans-Günter SchallerAxel SchlittStefan ReichertPublished in: Mediators of inflammation (2021)
SNPs in CD14, NF-κΒ, TLR2, and TLR4 are no risk modulators for preexisting CV events or severe periodontitis in CV patients. The CT genotype of CD14 SNP rs2569190 provides prognostic value for further CV events within 3 years of follow-up.
Keyphrases
- cardiovascular disease
- genome wide
- toll like receptor
- inflammatory response
- immune response
- computed tomography
- newly diagnosed
- nk cells
- small molecule
- ejection fraction
- signaling pathway
- type diabetes
- prognostic factors
- magnetic resonance imaging
- lps induced
- oxidative stress
- dna methylation
- copy number
- coronary artery disease
- early onset
- image quality
- patient reported outcomes
- contrast enhanced
- transcription factor
- patient reported
- drug induced
- electronic health record
- cardiovascular events