Genetic polymorphism in C3 is associated with progression in chronic kidney disease (CKD) patients with IgA nephropathy but not in other causes of CKD.
Sara T IbrahimRajkumar ChinnaduraiIbrahim AliDebbie PayneGillian I RiceWilliam G NewmanEman AlgoharyAhmed G AdamPhilip A KalraPublished in: PloS one (2020)
The C3 variant R102G is associated with progression of CKD in patients with IgA nephropathy.