Identification of neutrophil phenotype categories in geriatric hip fracture patients aids in personalized medicine.
Thomas M P NijdamBernard N JukemaEmma J de FraitureRoy SpijkermanHenk Jan SchuijtMarcia SpoelderCoen C W G BongersMaria T E HopmanLeo KoendermanFalco HietbrinkDetlef van der VeldePublished in: OTA international : the open access journal of orthopaedic trauma (2023)
Using point-of-care fully automated flow cytometry to analyze the neutrophil compartment in geriatric hip fracture patients is feasible and holds clinical value in determining patients at risk for adverse outcome. This study is a first step toward immuno-based precision medicine for identifying geriatric hip fracture patients that are deemed fit for surgery.
Keyphrases
- hip fracture
- end stage renal disease
- chronic kidney disease
- newly diagnosed
- prognostic factors
- peritoneal dialysis
- machine learning
- emergency department
- coronary artery disease
- high throughput
- atrial fibrillation
- percutaneous coronary intervention
- patient reported
- antiretroviral therapy
- adverse drug
- bioinformatics analysis