Effect of intensive blood pressure control on subtypes of mild cognitive impairment and risk of progression from SPRINT study.
Sarah A GaussoinNicholas M PajewskiGordon CheluneMaryjo L ClevelandMichael G CroweLenore J LaunerAlan J LernerJennifer Martindale-AdamsLinda O NicholsPaula K OgrockiBonnie C SachsKaycee M SinkMark A SupianoVirginia G WadleyValerie M WilsonClinton B WrightJeff D WilliamsonDavid M ReboussinStephen R RappPublished in: Journal of the American Geriatrics Society (2021)
Intensive treatment reduced the risk for amnestic and multi-domain subtypes of MCI. An adjudication of MCI was associated with increased risk of progression to dementia and death, highlighting the relevance of MCI as a primary outcome in clinical and research settings.