Sex differences in trigeminal neuralgia: a focus on radiological and clinical characteristics.
Gianfranco De StefanoDaniel LitewczukCristina MollicaGiuseppe Di PietroEleonora GalosiCaterina LeonePietro FalcoMaria Giulia TulloFrancesca CaramiaAndrea TruiniGiulia Di StefanoPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2023)
The preponderance of TN in the female sex and the association between idiopathic TN and the female sex suggest the role of additional etiological factors in the framework of a multi-hit model. The identification of clinical variables predicted by sex suggests the possibility that distinct phenotypes, with peculiar pathophysiological and therapeutic aspects, may occur in females and males.
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