Interplay Between Inflammatory-immune and Interleukin-17 Signalings Plays a Cardinal Role on Liver Ischemia-reperfusion Injury-Synergic Effect of IL-17Ab, Tacrolimus and ADMSCs on Rescuing the Liver Damage.

Sheung-Fat KoYi-Chen LiPei-Lin ShaoJohn Y ChiangPei-Hsun SungYi-Ling ChenHon-Kan Yip

Published in: Stem cell reviews and reports (2023)

Our results obtained from circulatory, pathology and molecular-cellular levels delineated that acute IRI was an intricate syndrome that elicited complex upstream and downstream inflammatory and immune signalings to damage liver parenchyma that greatly suppressed by combined tacrolimus and ADMSCs therapy.

Keyphrases

oxidative stress
ischemia reperfusion injury
liver failure
extracorporeal membrane oxygenation
respiratory failure
intensive care unit
drug induced
case report
bone marrow
mesenchymal stem cells
mechanical ventilation