E4orf1 improves adipose tissue-specific metabolic risk factors and indicators of cognition function in a mouse model of Alzheimer's disease.

Md Shahjalal Hossain KhanMarleigh HefnerArubala ReddyNikhil V Dhurandhar Vijay K Hegde

Published in: Nutrition & diabetes (2023)

This study opens-up the possibility of addressing glycemic control and steatosis for attenuating obesity-related cognitive decline. It also underscores the potential of E4orf1 for the purpose, which needs further investigations.

Keyphrases

cognitive decline
glycemic control
insulin resistance
mild cognitive impairment
adipose tissue
type diabetes
risk factors
mouse model
weight loss
high fat diet
high fat diet induced
metabolic syndrome
blood glucose
skeletal muscle
weight gain
physical activity
body mass index
multiple sclerosis
risk assessment