Login / Signup

Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity.

Sio-Hong LamPo-Hsun ChenHsin-Yi HungTsong-Long HwangChih-Chao ChiangTran Dinh ThangPing-Chung KuoTian-Shung Wu
Published in: Molecules (Basel, Switzerland) (2018)
Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical methods. Among the isolates, fifteen compounds were examined for their anti-inflammatory potential in vitro. The results showed that several compounds displayed moderate inhibition of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
Keyphrases
  • anti inflammatory
  • liquid chromatography
  • high glucose
  • high resolution
  • hydrogen peroxide
  • mass spectrometry
  • drug induced
  • ms ms