Predicting clinical progression and cognitive decline in patients with relapsing-remitting multiple sclerosis: a 6-year follow-up study.
Karolina KaniaMikołaj A PawlakMaria ForyckaMonika Wiłkość-DębczyńskaSławomir MichalakAgnieszka ŁukaszewskaAleksandra WyciszkiewiczAleksandra WypychZbigniew SerafinJustyna MarcinkowskaWojciech KozubskiAlicja Kalinowska-ŁyszczarzPublished in: Neurologia i neurochirurgia polska (2024)
Brain volume is an important predictor of future EDSS and cognitive functions outcome. MS patients have a potential for improving in neuropsychological tests over time. It remains to be established whether this is related to successful disease modification with immunotherapy. Baseline volumetric measures are stronger predictors of cognitive performance than relapse activity, which yet again highlights the importance of atrophy in MS prognosis.
Keyphrases
- multiple sclerosis
- cognitive decline
- white matter
- mild cognitive impairment
- end stage renal disease
- ejection fraction
- newly diagnosed
- chronic kidney disease
- mass spectrometry
- ms ms
- patient reported outcomes
- prognostic factors
- systemic lupus erythematosus
- risk assessment
- disease activity
- rheumatoid arthritis
- current status
- human health
- patient reported