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Contrast media timing optimization for coronary CT angiography: a retrospective validation study in swine.

Logan HubbardShant MalkasianYixiao ZhaoPablo AbbonaSabee Molloi
Published in: European radiology (2022)
• This study in swine retrospectively developed the mathematical basis of an improved approach for optimal contrast media timing in CCTA. • By combining dynamic bolus tracking with a simple contrast injection timing relation, CCTA can be acquired at the peak of the aortic root enhancement. • CCTA acquisition at the peak of the aortic root enhancement should maximize the coronary enhancement and CNR, potentially improving the accuracy of CT-based assessment of coronary artery disease.
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