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A hypercoagulable state leading to venous limb gangrene associated with occult lung adenocarcinoma.

Matthew Malcolm Andrew WaiteAnthony W MartinelliStephen Denis PrestonEmma GudginEmily SymingtonRobert C RintoulAdam PerytPatrick CoughlinPaul HayesDavid GilliganMartin Besser
Published in: Clinical case reports (2019)
We report a case of lung adenocarcinoma-associated hypercoagulability leading to venous limb gangrene, managed successfully with argatroban and then dabigatran. Use of idarucizumab permitted diagnostic investigations, leading to targeted antineoplastic therapy with crizotinib, surgical resection with curative intent, and continued survival over 2 years after the index event.
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