Lentivirus-Mediated VEGF Knockdown Suppresses Gastric Cancer Cell Proliferation and Tumor Growth in vitro and in vivo.
Jong-Hyung ParkJin-Hee SeoHee-Yeon JeonSun-Min SeoHan-Kyul LeeJin-Il ParkJun Young KimYang Kyu ChoiPublished in: OncoTargets and therapy (2020)
The constructed ShVEGF showed significant inhibition of NCI-N87 gastric cancer cell growth both in vitro and in vivo. These experimental results suggest a novel therapeutic strategy for patients with gastric cancer using lentivirus-mediated shRNA targeting VEGF.