Cortical development in fetuses with congenital heart defects using an automated brain-age prediction algorithm.

Sheila M P EverwijnAna I L NambureteNan van GelovenFenna A R JansenAris T PapageorghiouAlison J NobleAalbertine K K TeunissenLieke RozendaalNico A BlomJan M M van LithMonique C Haak

Published in: Acta obstetricia et gynecologica Scandinavica (2019)

This study shows that fetuses with isolated cases of congenital heart defects show some delay in cortical maturation as compared with healthy control cases. The clinical relevance of this small difference is debatable. This finding was consistent throughout pregnancy and did not progress during the third trimester.

Keyphrases

gestational age
preterm birth
pregnancy outcomes

machine learning
white matter

resting state
pregnant women

multiple sclerosis
cerebral ischemia