High-Resolution Ion Mobility Spectrometry Mass Spectrometry for Isomeric Separation of Prostanoids after Girard's reagent T Derivatization.
L LamontDarya HadaviA P BowmanB FlindersD Cooper-ShepherdMartin E PalmerJ JordensY MengerinkM HoningJ LangridgeT Porta SiegelRob J VreekenR M A HeerenPublished in: Rapid communications in mass spectrometry : RCM (2022)
The applied derivatization strategy offers high sensitivity and improved stereoisomeric separation for screening of complex biological systems. The high-resolution IMS comparison indicated that the best sensitivity and resolution are achieved by linear and nonlinear IMS, respectively.
Keyphrases
- liquid chromatography
- high resolution
- mass spectrometry
- tandem mass spectrometry
- gas chromatography
- high resolution mass spectrometry
- high performance liquid chromatography
- ultra high performance liquid chromatography
- simultaneous determination
- solid phase extraction
- capillary electrophoresis
- gas chromatography mass spectrometry
- liquid chromatography tandem mass spectrometry
- single molecule
- neural network