SERPINA1 methylation and lung function in tobacco-smoke exposed European children and adults: a meta-analysis of ALEC population-based cohorts.

Anna B Beckmeyer-BorowkoMedea ImbodenFaisal I RezwanMatthias WielscherAndre F S AmaralAyoung JeongEmmanuel SchaffnerJuha AuvinenSylvain SebertVille KarhunenRobert BettschartAlexander TurkMarco PonsDaiana StolzFlorian KronenbergRyan ArathimosGemma C SharpCaroline ReltonAlexander J HendersonMarjo-Riitta JarvelinDeborah JarvisJohn W HollowayNicole M Probst-Hensch

Published in: Respiratory research (2018)

The results do not support a role of SERPINA1 gene methylation as determinant of lung function across the life course in the tobacco smoke exposed general population exposed.

Keyphrases

lung function
cystic fibrosis
chronic obstructive pulmonary disease
air pollution
genome wide
dna methylation
young adults
copy number