MicroRNA-141-3p attenuates oxidative stress-induced hepatic ischemia reperfusion injury via Keap1/Nrf2 pathway.

Tingting LiQingsong ChenJiangwen DaiZuotian HuangYunhai LuoTong MouJunliang PuHang YangXufu WeiZhongjun Wu

Published in: Molecular biology reports (2022)

Our results indicate that miR-141-3p plays a major role in hepatic IRI through the Keap1 signaling pathway, and the present study suggests that miR-141-3p might have a protective effect on hepatic IRI to some extent.

Keyphrases

ischemia reperfusion injury
signaling pathway
oxidative stress
protein protein
induced apoptosis
cell proliferation