Human umbilical cord mesenchymal stem cells deliver exogenous miR-26a-5p via exosomes to inhibit nucleus pulposus cell pyroptosis through METTL14/NLRP3.
Xiaoqiu YuanTiefeng LiLei ShiJinhao MiaoYongfei GuoYu ChenPublished in: Molecular medicine (Cambridge, Mass.) (2021)
The results of the current study revealed the beneficial effects of hucMSC exosomes on NP cells and determined a potential mechanism inducing IVDD.