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Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review.

Beatriz Barreto-DuarteFabiana H Andrade-GomesMaría B ArriagaMariana Araújo-PereiraJuan Manuel Cubillos-AnguloBruno Bezerril Andrade
Published in: PloS one (2021)
The available evidence suggests that CVDs are related with the progression of NF-1, even in the absence of a clear clinical manifestation. In addition, improved prognosis was observed when imaging tests were performed to screen for cerebrovascular alterations early during the clinical investigation. Early diagnosis of CVD in NF-1 patients foster implementation of timely interventions, directly impacting clinical outcomes.
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