Association between neurofibromatosis type 1 and cerebrovascular diseases in children: A systematic review.
Beatriz Barreto-DuarteFabiana H Andrade-GomesMaría B ArriagaMariana Araújo-PereiraJuan Manuel Cubillos-AnguloBruno Bezerril AndradePublished in: PloS one (2021)
The available evidence suggests that CVDs are related with the progression of NF-1, even in the absence of a clear clinical manifestation. In addition, improved prognosis was observed when imaging tests were performed to screen for cerebrovascular alterations early during the clinical investigation. Early diagnosis of CVD in NF-1 patients foster implementation of timely interventions, directly impacting clinical outcomes.
Keyphrases
- end stage renal disease
- signaling pathway
- chronic kidney disease
- lps induced
- ejection fraction
- newly diagnosed
- primary care
- oxidative stress
- high resolution
- healthcare
- pi k akt
- nuclear factor
- young adults
- physical activity
- high throughput
- peritoneal dialysis
- quality improvement
- toll like receptor
- photodynamic therapy
- mass spectrometry
- patient reported