Elevation of Donor-derived Cell-free DNA Before Biopsy-proven Rejection in Kidney Transplant.

Jonathan S BrombergSuphamai BunnapradistMilagros Samaniego-PicotaSanjiv AnandErik StitesPhilippe GauthierZachary DemkoAdam PrewettMadeleine Armer-CabralKyle MarshallNavchetan KaurMichelle S BloomHossein TabrizianiSangeeta BhoradeMatthew Coopernull null

Published in: Transplantation (2024)

These data indicate that dd-cfDNA is an early indicator of biopsy-proven rejection, especially ABMR, suggesting a greater role for dd-cfDNA in surveillance to identify patients at high risk of ongoing or future rejection, thus requiring closer monitoring, biopsy, or other management changes.

Keyphrases

ultrasound guided
fine needle aspiration
public health
current status
big data
deep learning
artificial intelligence