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Establishment of a trastuzumab-resistant extramammary Paget disease model: loss of PTEN as a potential mechanism.

Che-Yuan HsuTeruki YanagiTakuya MaedaHiroshi NishiharaTakeru FunakoshiKodai MiyamotoRiriko IwamotoKenzo TakahashiHideyuki Ujiie
Published in: British journal of cancer (2024)
This study demonstrates an innovative TR EMPD-PDX model and introduces promising antineoplastic effects with various treatments for TR EMPD tumours.
Keyphrases
  • cell proliferation
  • epidermal growth factor receptor
  • pi k akt
  • signaling pathway
  • climate change