Adherence to treatment with prescribed topical corticosteroid therapy and potential barriers to adherence among women with vulvar lichen sclerosus: a prospective cross-sectional study.

Lichen sclerosus (LS) is a chronic inflammatory dermatosis that predominantly affects the anogenital region. Potential complications of vulvar LS include scarring, loss of architecture and vulvar squamous cell carcinoma (SCC). It has been suggested that individualised treatment regimens with long-term topical corticosteroid (TCS) may modify the course of disease in LS and reduce the risk of complications, such as SCC. Guidelines for the management of LS now advocate consideration of an individualised treatment regimen of long-term TCS to maintain disease control.