Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test.
Qing SunJonathan LiHui RenLarry PastorYulia LoginovaRoberta MadejKristopher TaylorJoseph K WongZhao ZhangAiguo ZhangChuanyi M LuMichael Y ShaPublished in: PloS one (2021)
The studies demonstrated that the QuantiVirus™ SARS-CoV-2 test has a LOD of 200 copies/mL in contrived saliva samples. The clinical performance of saliva-based testing is comparable to that of NPS-based testing. Pooling of saliva specimens for SARS-CoV-2 detection is feasible. Saliva based and high-throughput QuantiVirus™ SARS-CoV-2 test offers a highly desirable testing platform during the ongoing COVID-19 pandemic.