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Saliva as a testing specimen with or without pooling for SARS-CoV-2 detection by multiplex RT-PCR test.

Qing SunJonathan LiHui RenLarry PastorYulia LoginovaRoberta MadejKristopher TaylorJoseph K WongZhao ZhangAiguo ZhangChuanyi M LuMichael Y Sha
Published in: PloS one (2021)
The studies demonstrated that the QuantiVirus™ SARS-CoV-2 test has a LOD of 200 copies/mL in contrived saliva samples. The clinical performance of saliva-based testing is comparable to that of NPS-based testing. Pooling of saliva specimens for SARS-CoV-2 detection is feasible. Saliva based and high-throughput QuantiVirus™ SARS-CoV-2 test offers a highly desirable testing platform during the ongoing COVID-19 pandemic.
Keyphrases
  • sars cov
  • high throughput
  • respiratory syndrome coronavirus
  • real time pcr
  • loop mediated isothermal amplification
  • label free
  • quantum dots