Single-cell transcriptomics analysis of mild cognitive impairment in World Trade Center disaster responders.

Pei-Fen KuanSean CloustonXiaohua YangChang CheSamuel GandyRoman KotovEvelyn BrometBenjamin J Luft

Published in: Alzheimer's & dementia (Amsterdam, Netherlands) (2021)

Our findings suggested monocytes may constitute a key cell type to target in blood-based biomarker studies for early detection of risk of MCI and development of new interventions.

Keyphrases

mild cognitive impairment
single cell
cognitive decline
rna seq
high throughput
physical activity
dendritic cells
peripheral blood
case control