Reductive Metabolism of Xanthohumol and 8-Prenylnaringenin by the Intestinal Bacterium Eubacterium ramulus.
Ines L ParaisoLayhna S PlagmannLiping YangRyszard ZielkeAdrian F GombartClaudia S MaierAleksandra E SikoraPaul R BlakemoreJan Frederick StevensPublished in: Molecular nutrition & food research (2018)
Microbial metabolism is likely to affect both activity and toxicity of XN and derivatives. This study along with others highlights that attention should be focused on metabolites, in particular, products of intestinal microbial metabolism.